DOC

Low

By Gary Bryant,2014-06-03 03:57
9 views 0
Low

    Low

    work,theCASresearchershave beensucceededindeveloping aseriesofkeytechnologics invO1vingtheP1ant'SSeed germination,seedlingemergence, MedicineandHealth

    boltingpromotion,floweringand pestcontro1.Itisthefirstsuccessin theworldincompletingtheherb'S livingcycleinagreenhouse. Accordingtoexperts,the

    successnotonlyfillsaresearch gapintheintroductionofanalien herbaldrug,butalsoprovidesa technicalguidanceforlargescale

    breedingofvaluabledrugs.- LoWdosesOtaredwineIn!:IredIentfight-0,0????0

    diabetesinmice

    A

    intheskinsofredgrapesand insulin,accordingtoareportin developmentofType2diabetes, thefindings''provideapotential newtherapeuticapproachfor preventingortreating"both TheresearchgroupalSO

    tolongevity,DNArepair,and 14BulletinoftheChineseAcademyofSciences

    Theresultssuggestthat''red winemighthavesomebenefits foriusulinSensitivity.butit needstobeconfirmedbyfurther investigation,"saidZhai.Giventhe potentialcomplicationsofdrinking alcohol,"anevenbetteroption maybetofindothernaturalfoods enrichedwithresveratrolorfoods supplementedwithresveratrol," headded,notingthatthechemical iSalsoanactiveingredientin otherplants,includingonecalled Polygonumcuspidatumusedin traditionalChineseandJapanese medicine.

    Diabetesmellitus,themost commonendoCrinediSOrder, currentlyaffectsmorethan170 millionpeopleworldwideand isexpectedtoaffectmorethan 353millionbytheyear2030, ZhaiSaid.Type2diabeteS,

    whichaccountsformorethan 90percentofdiabetescases,is characterizedbytheresistanceof bodytissuestostimulationbythe peptidehormoneinsulin.Insulin

    normallylowersbloodglucose levelsbyfacilitatingthesugar'S uptake,mainlyintoskeletal muscleandfattissue,andby inhibitingglucoseproductionin theliver.Currently,alleviating insulinresistanceiSstilloneof thekeyavenuestotreatingType 2diabetes.

    Earlierstudieshadreporteda connectionbetweenSIRT1andthe processesofglucosemetabolism andinsulinsecretion.However. whetherSIRT1Wasdirect1Y

    involvedininsulinsensitivity remainedlargelyunknown,the

researcherssaid.

    Now,theresearchersreport thatSIRTllevelsarereducedin insulin.resistantcellsandtissues andthattreatmentsthatblockthe enzyme'sfvInctionleadtoinsulin resistance.Furthermore,increased SIRT1activityimprovedinsnlin sensitivity.Similarly,resveratrol-- atadoseofjust2.5mg/kg/day

    enhancedinsulinsensitivityin cells.Thatlowdoseofresveratrol alsoreducedinsulinresistancein

    animalsfedahigh-fatdiet,the researchersshowed.

    ''WefoundSIRT1improves

    insulinsensitivity,especiallyunder insulin.resistantconditions."Zhai PsychOlOgy

    P

    said."Furthermore,we

    foundthatresveratrol,

    atavery1owdose

    comparedwithmany

    Previousstudies,

    improvesinsu1in

    sensitivityviaSIRT1.''

    Thefindings

    suggestthatthosewho

    drinkredwinefor

    thehealthpromoting

    benefitsofresveratrolmight"think aboutdrinkingless."Zhaisaid. Previously,henoted,theeffects ofresveratrolseeninmicehad impliedthathumansmightneedto drinkaboutl20litersofredwine eachdaytogetenoughresveratrol toenioYthesamebenefit.

    "Accordingtoourfindings,people mightneedtodrinkaboutthree litersofredwineeachdaytoget sufficientresveratrol--about15

    mgforitsbiologicaleffects." (Source:CellPress)

    Prevalenceofsoftneurologicalsigns inChinesepeople

    rof.RaymondC.K.Chen,

    aneuropsYcho1ogist

    withtheCASInstitute

    ofPsychology,hasmadenovel Progressinhisstudiesof

    schizophfenia.Hisworkhas beenreportedbyarecentissueof BehaviouralNeurology.

    Neurologicalsoftsigns(NSS) areminor('soft')neurological abnormalitiesinsensoryandmotor performanceidentifiedbyclinical examination.Theyareconsidered targetfeaturesforpatientswith schizophrenia,amajormental disordershowingabnormalitiesin perception,language,cognition, emotion.socialfunctionsand

    nervoussystem.However,the NSSmayalsobediscoveredin normalpeople,althoughthelevel isslight.Therefore,NSSstudies areimportantfortheindepth

    understandingofschizophrenia. Withanobjectiveof

    examiningtheprevalenceand

    typeofneurologicalsignsin Chinesepatientssufferingfrom schizophrenia,Prof.Chenand co?-workersemployedacross?- sectionaldesignwiththeaidofthe CambridgeNeurologicalInventory (CNI).TheCNIiscomprisedof sevensubscales,includingmotor coordination,sensoryintegration, disinhibition,extrapyramidal signs,dyskinesia,catatonia,and pyramidalsigns.Theformerthree subscaleswereclassifiedassoft signs,whereasthelatterfour subscaleswereclassifiedashard signs.

    Thestudy,involving250

    Chineseschizophrenicpatientsand 90normalcontrols,discovered thathighlevelsofneurological abnormalitycharacterize

    schizophrenicpatientsinChina.An extendedassessmentbatteryofCNI providesevenbetterdiscrimination ofpatientsfromnormalcontrols, andsoftsignsaremorestrongly associatedwiththediseasethan hardsignsintheChinesesample.

    BulletinoftheChineseAcademyofSciences15

Report this document

For any questions or suggestions please email
cust-service@docsford.com