A serum vitamin A (VA)
1.1 Method and reference values
Spectrophotometry: Adult 1.12 ~ 3.14μmol / L, children, 0.87 ~
150μmol / L.
1.2 Clinical Significance
1.2.1 Vitamin A in two ways. One is the vitamin A alcohol, the other is β-carotene, in human small intestine and liver can be transformed into a active vitamin A.
1.2.2 Vitamin A has a wide range of physiological effects, can promote the growth and development, the maintenance of normal epithelial
tissue structure and function, and to participate in the visual effects, enhance the skin and mucosal barrier resistance. Vitamin A deficiency can cause growth and developmental disorders, dry and epithelial cells, epidermal keratinocytes, so as to eyes, digestive tract, respiratory tract and other epithelial tissue is particularly evident.
1.2.3 increased: Baby found in spontaneous hypercalcemia, vitamin A poisoning, chronic glomerular nephritis, nephrotic syndrome, diabetes,
1.2.4 reduction: seen in night blindness, dry eye, hepatitis, cirrhosis, pancreatic function reduce malabsorption syndrome, and so on.
2 serum vitamin B1 (VitBl)
2.1 Method and reference values
Fluorescence (FL): 16.7 ~ 50.0μmol / L.
2.2 Clinical Significance
2.2.1 Vitamin B1 in the liver and the reaction of sulfur acid pyrophosphate coke phosphate (TPP), TPP is the oxidation of α-keto acid
decarboxylase Department of coenzyme involved in oxidation of α-keto acid
decarboxylation role in the maintenance of normal glucose metabolism and nerve and muscle function of great significance.
2.2.2 Vitamin B2 deficiency glucose metabolic intermediate pyruvate oxidation blocked Gang had gathered, resulting in nerve tissue of the body source of energy barriers, there beriberi disease, manifested as numbness of extremities, muscle atrophy, lower limb edema. In addition, also enables the activity of AChE increased, affecting nerve conduction,
causing gastric peristalsis slowed down to reduce secretion of digestive juice, there loss of appetite, indigestion and other symptoms.
2.2.3 Vitamin B6 deficiency in patients occurred mainly in order to milled rice-eating areas.
2.2.4 reduction: seen in beri-beri, multiple neuritis, heart
failure, hyperthyroidism and diarrhea.
3 serum vitamin B2 (VitB2)
3.1 Method and reference values
Fluorescence: 70 ~ 100μmol / L.
3.2 Clinical Significance
3.2.1 active form of vitamin B1 in the body, there are two, namely, flavin mononucleotide and flavin adenine dinucleotide, is a reductase in vivo oxidation of the coenzyme, in the bio-oxidation process
in the body plays a role in delivery of hydrogen. Can promote the protein, sugar, fat metabolism, but also can reduce the incidence of cardiovascular and cerebrovascular diseases, diuretic swelling, prevention and treatment
3.2.2 reduction: common in corneal vascularization, seborrheic
dermatitis, scrotal inflammation, angular cheilitis, glossitis, cheilitis, oral mucosa ulcers.
4 Determination of plasma pantothenic acid (VitB3)
4.1 Method and reference values
Colorimetry: 1.74 ~ 2.49μmol / L.
4.2 Clinical Significance
4.2.1 constitute coenzyme A, pantothenic acid composition of the body of sugar, lipid and protein metabolism has a very significant impact. Able to maintain normal human cells, development, maintenance and control.
Normal adrenal function. Reposted elsewhere in the paper for free download http://