Axial length and age-related analysis of cataract surgery_2619

By Anne Wallace,2014-10-30 10:46
10 views 0
Axial length and age-related analysis of cataract surgery_2619

Axial length and age-related analysis of cataract surgery

     Author: WU Chang-fan Cairui Ling Bao-Ling

    Huang, Hsu Chin-Lang Ping

     Abstract Objective: To observe the cataract surgery in patients with the relationship between age and axial length. Methods: The hospital 2001/2004 1 004 cases of primary cataract surgery in patients with age, axial length, according to axial length of the points A, B, C 3 groups, each group compared operative age, and age and axial length of the

    surgery for correlation analysis. Results: The axial length of C, cataract surgery in patients with a mean age (64.25 ? 8.0)

    years, while the axial length of A group, the average age of surgery was only 67.44 ? 9.16 years, significantly different

    (P = 0.002). Surgery age and axial length of a weak negative correlation, r =- 0.25, P = 0.015. Conclusion: With the

    increase of axial length of cataract surgery in patients with younger age at the trend.

     Key words age, axial length of cataract surgery

     Changes in axial length and age at cataract surgery in Chinese

     Abstract AIM: To investigate the relation of axial length and the age of patients undergoing cataract.Methods:

Ages and axial lengths of 1 004 patient undergone cataract

    surgery from 2001 to 2004 were recorded and collected. The patients were divided into three groups (A, B and C) according to the axial length. The age at cataract surgery and correlation between age and axial length were analyzed. RESULTS: The means age (years) at cataract surgery in group C was significantly lower than that in group A (64.25 ? 8.0vs

    67.44 ? 9.16, P = 0.002). There are less significant

    correlation between the age at cataract surgery and the axial length (r =- 0.25, P = 0.015). CONCLUSION: Age at cataract

    surgery tends to become lower with the increasing of the axial length of the eye.

     * KEYWORDS: cataract surgery; age; axial lengths

     0 Introduction

     With the population growth and aging, our age-related

    sharp increase in the proportion of cataract patients; Similarly, the proportion of myopia in China also showed an increasing trend, especially in young people, the world's second highest prevalence rate of myopia, the actual total the number of the world. In myopia, myopia with axial predominance

    of the formation of axial myopia will produce more changes in the structure of the eye, while increasing the appearance of eye-related complications: glaucoma, cataract, retinal detachment and so on, a serious threat to vision health. At

    present, China's current population is cataract treatment, has been the impact of myopia is not known. Retrospective analysis of our hospital is now nearly 3a, the treatment of cataract patients, the axial length changes and cataract surgery in the

    correlation between age.

     An object and method

     1.1 The objects collected from the 2001-01/2004-12

    cataract patients admitted to our hospital for the diagnosis, there are glaucoma, grape inflammation, diabetic retinopathy, retinal detachment, a clear history of eye trauma, except in

    order to diagnose patients with senile cataract as the main collection of objects, some patients do not collect relevant factors, such as: smoking, alcohol consumption, and non-

    diabetic retinopathy patients. A total of 1 004 cases, mean

    age of 67.10 ? 9.07 years, male 497, female 507, 503 cases of the right eye, left eye 501 cases.

     1.2 ways to use the French BVI-A / B Ultra-eye axial

    length measurement of each eye measured five times, take average of axial length, Topcon KR-8800 measurement of corneal

    curvature, and calculate the intraocular lens in degrees; B super-observation of vitreous and retina of ; the use of STAT 8.0 software analysis and processing data: according to axial length of the points A, B, C group (A, axial length AL ?

    25mm; B Group 25mm <AL?30mm;CGroupAL> 30mm), Comparison of

    treatment of age ; with the scatter observation of cataract surgery the correlation between age and axial length. Reposted elsewhere in the paper for free download http://

     2 Results

     2.1 The average axial length of axial group 24.72 ?

    2.74mm. Comparison according to axial length can be seen in the longer axial length C, the average age of cataract surgery 64.25 ? 8.04 years, compared with group A the average age of

    cataract surgery 67.44 ? 9.16 years, the two groups were

    significantly different, P = 0.002 . Table 1.

     2.2 The age group with increasing age, axial length change in the short trend, but no statistically significant difference (P = 0.05 ~ 0.63), Table 2.

     2.3 The age and axial length of the scatter plot with the growth of axial length, we can see the age of cataract surgery is gradually smaller, the regression equation y = 73.32-0.25x

    (t =- 2.43, p = 0.015), operative age, and axial length has a

    weak correlation.

     Figure 1 cataract surgery in patients with age and axial length of the scatter plot

     3 Discussion

     Senile cataract blindness in China's current primary eye disease, population growth and aging makes the sharp rise in

    the number of cataract is still the best way to resolve through the surgery to see again [1-3]. Epidemiological

    research suggests that a large number of senile cataract formation more risk factors: smoking, alcohol consumption, ultraviolet radiation, such as diabetes and corticosteroids [4], but the exact cause of the disease is not clear. Cataract and refractive error correlation between the reports [5,6] is greater: cortical cataract may appear astigmatism change; nuclear cataract can cause progression of myopia; a high

    degree of myopia and cataract formation are relevant, medium and low degree of myopia associated with cataract formation is still in dispute. Myopia may be the mechanism leading to cataract [7,8] is: the regulatory power of myopia declined,

    making ciliary muscle contraction Erzhi excessive increase in pressure on the lens, while contraction will pull the lens peripheral fiber separation. In patients with high myopia lens, the decline in antioxidant capacity, increased oxidation

    of unsaturated lipids. Myopia lens thinning, increased pressure on the fibrous tissue that can make cataract formation. Axial myopia increases, making back room at the same time to deepen and change the lens metabolism.

     Through retrospective analysis, we can see: axial length increased, especially in the axial length> 30mm, the cataract surgery at the age of 64.25 ? 8.04 years, shorter axial

    length of cataract surgery age 67.44 ? 9.14 years ahead of

    time in recent 3a ( P = 0.002); axial and surgical correlation

    of age with a weak correlation (r =- 0.25), Tuft SJ et al [9]

    in the European patient population observed in a stronger correlation: Cataract surgery in patients with axial and age, the negative correlation of 1.56. The results suggest that as

    China's population increased in patients with myopia will lead to an already aging population due to cataracts caused by further increase in the number of people, particularly in

    younger age cataract surgery, will make our task more difficult the existing Prevention of Blindness , and thus to prevent and delay the development of myopia is also urgent.

     In this study only the tips of axial length and a weaker correlation cataract surgery, and this retrospective study data only from in-patient population-based, and do not

    represent the natural population as the object of studying the situation; Besides, this investigation did not collect other confounding factors, including: smoking, alcohol consumption, vitamin use, etc., while the age at different stages of

    cataract surgery in patients with preoperative visual acuity of the request, nor for analysis. A population-based surveys

    or case-control study, rigorous assessment of the impact of myopia on cataract necessary.


     1 Zhao-liang. China's progress in prevention of blindness. Chinese Journal of Ophthalmology, 2005; 41:697-701

     2 Song Ce, Que Peng Zhi Kyoshi leather, Shen and white clouds, Xiao-Mei Chen. Super-old values of cataract extraction

    and intraocular lens into the 49 cases. International

    Ophthalmology, 2003; 3 (4) :105-106

     3 Zhu Li, Shen Nim Chi, Yi Ding, Wang Yan, Wu Lei, Zhu Min. Elderly senile cataract molecule clinical observation. International Ophthalmology, 2004; 4 (2) :331-333

     4 Mccarty CA, Mukesh BN, Fu CL, Taylor HR. The epidemiology of cataract in Australia. Am J Ophthalmol, 1999; 128:446-465

     5 Pesudovs K, Elliott DB. Refractive error changes in cortical, nuclear, and posterior subcapsular cataracts. Br J Ophthalmol ,2003,87:964-967

     6 Wong TY, Klein BEK, Klein R, Sandra CT, Kristine EL. Refractive errors and incident cataracts: the Beaver Dam Eye Study. Invet Ophthalmol Vis Sci, 2001; 42:1449-1454

     7 Micelli FT, Vendemiale G, Grattagliano I, Boscia F, Arnese L, Altomare E, Cardia L. Role of lipid peroxidation in the pathogenesis of myopic and senile cataract. Br J Ophthalmol, 1996; 80:840-843

     8 Zadink K, Mutti DO, Fusaro RE, Adams AJ. Longitudinal

    evidence of crystalline lens thinning in children. Invet Ophthalmol Vis Sci, 1995; 36:1581-1587

     9 Tuft SJ. Axial length and age at cataract surgery. J Cataract Refract Surg, 2004; 30:1045-1048 reposted elsewhere

    in the paper for free download http://

Report this document

For any questions or suggestions please email