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Astragalus, Atractylodes, wind, and Yu Ping Feng San study of trace elements in_588

By Leslie Ruiz,2014-10-30 10:40
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Astragalus, Atractylodes, wind, and Yu Ping Feng San study of trace elements in_588

    Astragalus, Atractylodes, wind, and Yu Ping Feng San study of trace elements in

     Authors: Zeng Liang, Chen mong lang, Wang Yan Lei, Yu Dan

     Abstract Objective To determine the Astragalus,

    Atractylodes, wind, and Yu Ping Feng San in the trace elements iron, copper, manganese, lead content and dissolution rate. Methods using flame atomic absorption spectrometry. Results decoction of Chinese medicine, the trace element contents are very different. Conclusion of each element in traditional

    Chinese medicine decoction of the content and dissolution rate varied, complex relationships between the two should be based on rational drug use in different clinical needs, in order to better play its efficacy.

     Key words Chinese medicine; trace element; atomic absorption spectrometry

     Study on Determination of Trace Elements in Huangqi, Baizhu, Fangfeng and Yupingfeng Decoction

     Abstract: ObjectiveTo determine the content and dissolved

    rates of Fe, Cu, Mn, Pb in Huangqi, Baizhu, Fangfeng and Yupingfeng decoction. MethodsThe determination was performed by flame atomic absorption spectrometry. ResultsThere was significant difference of trace elements content between the medical herb pieces and the herb decocted. ConclusionThe

    content and dissolved rates of 4 kinds of trace elements are different in the water decocted solution of the Chinese traditional medicines. It is necessary to apply the Chinese traditional medicines in different modes according to different clinical needs, in order to increase their curative effect.

     Key words: Chinese traditional medicines; Trace elements; Atomic absorption spectrometry

     Yu Ping Feng San is a Chinese name of righting and reinforce the classic side, is now commonly used in the

    treatment of spontaneous perspiration, cold, cough and asthma, children with recurrent upper respiratory tract infections, chronic bronchitis and other diseases [1]. Its prescription form as follows: wind 2 g, Astragalus, Atractylodes of 4 g.

    The present study, pairs of medicinal decoction direct digestion and digestion of the two methods, Astragalus, Atractylodes, wind, and Yu Ping Feng San iron, copper, manganese, lead and four kinds of trace elements were determined, and direct digestion Determination of the total content of trace elements in medicine as the standard for traditional Chinese medicine decoction of the dissolution rates of various trace elements are discussed, aimed Based on the findings to guide clinical use of drugs in order to better

    play to the efficacy of traditional Chinese medicine.

     An instrument and with the test drug

     1.1 Instrument TAS-986 atomic absorption

    spectrophotometer (Beijing General Instrument Co., Ltd. S & P analysis).

     1.2 reagent iron, copper, lead, manganese standard reserve liquid (Beijing Institute of the State Environmental Protection Administration of standard samples); nitric acid, hydrogen peroxide, were analytically pure; water twice distilled water; Astragalus, Atractylodes, wind purchased from the Hubei Co., Ltd. Chinese Herbal Pieces Jin-Gui.

     2 Methods and reagents

     2.1 Sample Handling

     The total content of trace elements in medicinal herbs 2.1.1 Determination of precision that take wind 2 g,

    Astragalus, Atractylodes of 4 g, were used nitric acid -

    hydrogen peroxide to the solution to clarify the digestive system, constant volume after the analyte.

     2.1.2 Determination of trace elements in water decoction of precision that take wind 2 g, Astragalus, Atractylodes of 4 g, respectively, add appropriate amount of water, soak 15 min post-heated to boiling, maintaining micro-boiling after 30 min

    filtration, the filtrate with nitric acid - hydrogen peroxide

    to the solution to clarify the digestive system of constant

    volume after the analyte. Then the weight of each flavor of herbs according to the above said four were taken, together decoction made of Yu Ping Feng San, in addition to maintain the micro-boiling time was 15 (A), 30 (B), 60 (C), and 90 min

    ( D), other ibid constant volume under test after treatment. Reposted elsewhere in the paper for free download http://

     2.2 The working conditions of instrument gas: acetylene; help gas: air; Source: hollow cathode lamp; wavelength: Fe

    248.3nm, Cu 324.7 nm, Mn 279.5 nm, Pb283.3nm.

     2.3 Samples will be each of these samples were determined by flame atomic absorption spectrometry was determined to

    calculate the water decoction of medicinal plants, and the content of each element, and the decoction of the dissolution rate of each element in the results shown in Table 1 ~ 2.

     2.4 Radix Astragali 3 recovery experiments were obtained using standard addition method to do the recovery of experimental results show that the average recoveries of all

    elements of 94.6% ~ 101.5%, and the relative standard deviation RSD ? 1.53%.

     Table 1 decoction of medicinal plants, and each element of the content (abbreviated)

     Table 2 decoction of the dissolution rate of each element (omitted)

     3 Discussion

     Traditional Chinese Medicine and the dissolution rate of trace elements in the research, not only directly shows the contents of trace elements and their state of existence, so as to provide the basis for evaluation of the quality of Chinese

    medicine, but also shows the dissolution rate of trace elements in decoction by the actual content, for the to guide clinical use of drugs has important practical significance [2]. Experimental results show that under the same conditions,

    medicinal herbs fried together after the dissolution of the amount of each element of each element is not a single fried dissolved after a simple sum, fried together after the iron, copper dissolution rate increases, while the manganese, lead and dissolution rate of was significantly reduced; Yu Ping Feng San dissolution rate of each element does not extend along with the boiling gradually increased, iron, copper dissolution rate and the boiling time to show a more complex relationship. For the same kinds of traditional Chinese

    medicine, the decoction of the dissolution rate of each

    element varied, and some even vary greatly, such as the dissolution rate of Atractylodes minimum of 11.05 percent, the largest up 52.26%; for the same element in terms of , due to

    the different types of traditional Chinese medicine and its dissolution rate is different, short, traditional Chinese medicine decoction of various trace elements in the relationship between content and dissolution rate of more complicated the process of its dissolution needs to be done more in-depth research to better guide the clinical use of drugs.

     References

     [1] High-power country, Bing Shou-lan. Fang Yu Ping

    Feng San and the use of analysis [J]. Shizhen country Sinopharm Medicine, 2006,17 (5): 839.

     [2] Shao Hong, Cai-Miao Bian. 7 kinds of trace elements in traditional Chinese medicine and tonic dissolution rate measurement [J]. Guangdong Trace Elements Science, 2002,9 (11): 53. Reposted elsewhere in the paper for free download

    http://

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