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Supplementary Table 1 Genes showing differential expression

By Gordon Smith,2014-11-25 19:13
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Supplementary Table 1 Genes showing differential expression

Supplementary Table 2: Gene Set Enrichment Analysis (GSEA). 177 gene sets were identified as sharing up-regulated genes with

    our data and 54 gene sets were identified as sharing down-regulated genes (NOM p-value ? 0.05 and FDR q-value ? 0.25).

    FWER Rank at Gene Set (Up-Regulated) Size ES NES NOM p-val FDR q-val p-val Max Leading Edge CARIES_PULP_UP 195 0.542 2.375 0 0.001 0.001 3690 tags=52%, list=21%, signal=66% CARIES_PULP_HIGH_UP 87 0.56 2.208 0 0.003 0.006 3878 tags=57%, list=22%, signal=73% TAKEDA_NUP8_HOXA9_3D_UP 177 0.493 2.137 0 0.005 0.016 2571 tags=36%, list=15%, signal=41% ERYTHPATHWAY 15 0.8 2.126 0 0.005 0.019 1517 tags=67%, list=9%, signal=73% LINDSTEDT_DEND_8H_VS_48H_UP 61 0.562 2.071 0 0.01 0.046 3773 tags=56%, list=22%, signal=71% CMV_HCMV_TIMECOURSE_12HRS_UP 25 0.65 2.051 0 0.012 0.07 3281 tags=60%, list=19%, signal=74% TSA_CD4_DN 17 0.719 2 0 0.023 0.145 2186 tags=53%, list=12%, signal=60% TAKEDA_NUP8_HOXA9_10D_UP 156 0.459 1.985 0 0.026 0.183 2005 tags=27%, list=11%, signal=30% SANA_TNFA_ENDOTHELIAL_UP 77 0.508 1.94 0 0.032 0.306 3315 tags=40%, list=19%, signal=49% CROONQUIST_IL6_RAS_UP 23 0.645 1.941 0 0.035 0.304 4406 tags=70%, list=25%, signal=93% UVB_NHEK1_UP 162 0.459 1.958 0 0.036 0.256 3509 tags=35%, list=20%, signal=43% IRITANI_ADPROX_DN 56 0.534 1.945 0.002 0.037 0.294 3314 tags=48%, list=19%, signal=59% IGF_VS_PDGF_DN 41 0.565 1.922 0 0.041 0.402 1366 tags=27%, list=8%, signal=29% UVB_NHEK1_C2 22 0.656 1.917 0 0.041 0.428 3509 tags=59%, list=20%, signal=74% DAC_PANC50_UP 40 0.575 1.912 0.002 0.041 0.455 2324 tags=35%, list=13%, signal=40% HINATA_NFKB_UP 105 0.466 1.882 0 0.048 0.597 3024 tags=35%, list=17%, signal=42% DAC_BLADDER_UP 26 0.613 1.891 0.002 0.049 0.564 1147 tags=35%, list=7%, signal=37% HBX_HCC_UP 16 0.678 1.894 0.002 0.049 0.545 1769 tags=44%, list=10%, signal=49% TAKEDA_NUP8_HOXA9_16D_UP 143 0.442 1.867 0 0.051 0.668 2770 tags=31%, list=16%, signal=37% HSA04950_MATURITY_ONSET_DIABETES_OF_THE

    _YOUNG 20 0.633 1.883 0 0.051 0.596 3814 tags=60%, list=22%, signal=77% TAKEDA_NUP8_HOXA9_8D_UP 135 0.445 1.868 0 0.052 0.665 2448 tags=31%, list=14%, signal=36% STEMPATHWAY 15 0.691 1.869 0 0.054 0.661 966 tags=53%, list=6%, signal=56% BRG1_SW13_UP 42 0.548 1.854 0 0.056 0.724 4893 tags=55%, list=28%, signal=76% HSA04740_OLFACTORY_TRANSDUCTION 30 0.572 1.83 0.002 0.07 0.823 973 tags=23%, list=6%, signal=25% GALINDO_ACT_UP 76 0.478 1.833 0 0.071 0.813 3521 tags=33%, list=20%, signal=41% TAKEDA_NUP8_HOXA9_6H_UP 76 0.48 1.82 0 0.076 0.867 2732 tags=36%, list=16%, signal=42% VERHAAK_AML_NPM1_MUT_VS_WT_UP 158 0.429 1.808 0 0.078 0.899 3328 tags=36%, list=19%, signal=44% HSA04640_HEMATOPOIETIC_CELL_LINEAGE 83 0.465 1.813 0 0.079 0.883 2277 tags=37%, list=13%, signal=43%

    TAKEDA_NUP8_HOXA9_10D_DN 139 0.43 1.801 0 0.08 0.922 1938 tags=30%, list=11%, signal=34% RUTELLA_HEPATGFSNDCS_UP 142 0.432 1.802 0 0.081 0.92 3495 tags=36%, list=20%, signal=45% YANG_OSTECLASTS_SIG 39 0.526 1.808 0 0.081 0.898 1529 tags=38%, list=9%, signal=42% AGEING_KIDNEY_UP 362 0.381 1.795 0 0.082