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Acupuncture and the treatment of diabetic peripheral neuropathy efficacy of_772

By Greg Holmes,2014-10-30 08:51
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Acupuncture and the treatment of diabetic peripheral neuropathy efficacy of_772

    Acupuncture and the treatment of diabetic peripheral neuropathy efficacy of

     Abstract Objective To observe the Acupuncture and

    treatment of diabetic peripheral neuropathy. Methods 86 patients with diabetic peripheral neuropathy were randomly

    divided into treatment group and control group, treatment group with acupuncture traditional Chinese medicine treatment, the control group treated with Mikebao. Results In the treatment group, the effective and efficient VS control group

    (P <0.05); treatment group, nerve conduction velocity of nerve conduction velocity VS control group (P <0.01). Conclusion Acupuncture and treatment of diabetic peripheral neuropathy is better than Western medicine treatment.

     Key words diabetic peripheral neuropathy treated with

    acupuncture traditional Chinese medicine treatment Methycobal

     Diabetic peripheral neuropathy (DPN) is a common complication of diabetes, one commonly used by western medicine Vitamin B family therapy (Methycobal the B12

    derivative), but the effects are less satisfactory. In 2003, the author of 44 patients were treated with injections, and methods used in treatment, and with Mikebao compared 42 patients treated, efficacy remarkable. Are reported below.

     1 Case Information

     1.1 Diagnostic Criteria

     86 patients were in 1999 WHO diagnostic criteria [1], type 2 diabetes mellitus (T2DM) patients, accompanied by pain in extremities, hair cool, clear case of cold, worse at night, feeling abnormal physical examination revealed nerve

    conduction velocity slow down, weakening or disappearance of tendon reflexes, cold perception threshold, vibration perception threshold increased. Due to the exclusion of other causes of peripheral neuropathy.

     1.2 In general

     Treatment group 44 cases, 42 cases of the control group. Two groups of patients with sex, age, duration, fasting blood glucose (FBG), glycosylated hemoglobin (HBA1C) in table 1. Information about the two groups statistically (χ2, t test)

    analysis, P> 0.05, comparable. Table 1 Comparison of two groups of patients with normal (omitted)

     Two treatment

     The original diet therapy, exercise therapy program remains unchanged, oral hypoglycemic drugs or insulin subcutaneous blood glucose control, control objectives for the FBG: (7.00 ? 1.00) mmol / L, postprandial 2 h blood glucose (2 h FBG): (10.00 ? 1.00) mmol / L.

     2.1 treatment group

     Acupuncture Chinese Herbal Therapy.

     2.1.1 acupuncture treatment under the master to take

    stomach Yu (Modern said pancreatic Yu), Pishu, stomach Yu, Zusanli, built-ri, air sea, Guan Yuan. Upper extremity lesions with points: Hegu, after River, within a closed, hand Third, the song pool; lower extremity lesions with points: Yung-

    chuan, tai chong, Kunlun, Sanyinjiao, Yin Ling Quan, Yang Ling-chuen. Imposed to mention a combination of acupuncture insertion twisting tactics reinforcing-reducing, get gas for

    the degrees, leaving needle 30 min, 1 time / d, 12 d for a course of treatment, rest 3 d, proceed to the next one course of treatment, a total of 4 courses.

     2.1.2 Chinese Herbal Therapy

     Party election Buyanghuanwu Decoction: Astragalus 30 g, Chinese angelica 15 g, Radix Paeoniae Rubra 15 g, Chuanxiong 15 g, earthworm 12 g, peach kernel 12 g, safflower 12 g, Achyranthes 20 g, Loranthaceae 20 g, Spatholobus 20 g, cinnamon 6 g. Decoction two times, juice 500 ml, mixing, sub-2

    doses, 1 / d, 15 d for a course of treatment, a total of 4 courses.

     2.2 in control group

     Oral Methycobal (Methycobal, Eisai China Pharmaceutical Company) sugar-coated tablet 0.5 mg, 3 times / d, according to symptoms, where it appears desirable, treatment with the former. Reposted elsewhere in the paper for free download http://

     3 Efficacy

     3.1 Efficacy Standards

     According to the guiding principles of Chinese medicine clinical research new drugs [2] to develop. Symptoms disappeared or significantly improved nerve conduction velocity (NCV) increased 5 m / s above are markedly; symptom

    improvement, NCV increased 1 ~ 5 m / s for the effective; symptom-free to reduce, NCV no change or decrease to be invalid.

     3.2 Results

     Table 2. Table 2 Comparison of efficacy of the two groups (omitted)

     3.3 NCV changes in Table 3. Table 3 before and after treatment and compared between the two groups NCV (omitted)

     4 Discussion

     Diabetic peripheral neuropathy (DPN) in the pathogenesis is not yet clear. Microangiopathy doctrine: diabetes caused by systemic microvascular basement membrane thickening, vascular endothelial cell proliferation, transparency change, while deposition of glycated hemoglobin, blood viscosity increased, erythrocyte, platelet aggregation, tiny blood vessels narrow, leading to nervous tissue ischemia and hypoxia, neurocutaneous disorder fat-based disease and improve limb blood circulation and oxygen to promote the blood supply, oxygen and energy supply of a fundamental treatment of the disease. Chinese believe that the course of time the disease diabetes, damage

    gas consumption Yin, Qi pushing of weakness, congestion blocking network Erzhi limb numbness, cold limbs, skin symptoms such as a wrong for etiology and pathogenesis, Expelling spleen Qi , Huayu Tong Luo. Under Yu Acupuncture

    stomach (pancreatic Yu) enables insulin secretion in response to earlier, this may be excited about the vagus nerve -

    insulin system to produce the [3], Pishu, stomach Yu, Zusanli, air sea, Guan Yuan, Jian-li spleen Yiwei, qi nourishing, and

    fundamentally the treatment of diabetes itself, with limb acupoint to stimulate through the air, promote blood

    circulation, thereby improving the blood supply nerve supply of oxygen, so that functional recovery of damaged nerves. BYHWD from Wang Qing-ren, "Doctor Lin Corrector." Astragalus

    qi Fang Sun; TPG, Chuanxiong, Chinese angelica, peach kernel, safflower blood circulation Huayu; Achyranthes, Loranthaceae, Millettia pass through the reach envelope; cinnamon Onyang of gas. Various drug combination, complement each other and

    played a total of qi blood circulation Huayu meridians of power. Clinical observations show that: Bu Yang Huan Wu Tang on diabetic peripheral neuropathy in patients with nailfold microcirculation morphology, flow pattern and the loop weeks have improved the situation the role of the active ingredient Astragalus Astragalus saponins can lower blood viscosity, inhibiting platelet aggregation, improve microcirculation [4]. Chuanxiong microcirculation in the TMP increase the number of open and reduce blood viscosity, inhibit thromboxane

    biosynthesis. Earthworm containing urokinase-type substances,

    with fibrinolysis activity. Acupuncture and the Treatment of DPN results showed that: compared with the control group both before and after, or their own, the difference was significant

    (P <0.01), total effective rate was 81.82%, nerve conduction velocity increased significantly, indicating the therapies for the treatment of diabetic peripheral neuropathy and effective methods.

     References

     [1] Xu Man-tone, LU Guang-hua, Chen Ming-dao.

    Diabetologia [M]. Shanghai: Shanghai Science and Technology Press, 2003:16.

     [2] The People's Republic of China Ministry of Health. TCM new drug clinical research guidelines [S] .1993:252.

     [3] Zhou Lu. Gastrointestinal Physiology [M]. Beijing: Science Press, 1991:766.

     [4] Gao Xuemin. In the pharmacy [M]. Beijing: People's Health Publishing House, 2000:1582. Reposted elsewhere in the paper for free download http://

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